Researchers from the Schulich School of Medicine & Dentistry analyzed the dorsal and ventral regions of the brain following THC exposure in rats and concluded that it may induce long-lasting memory impairment and increased anxiety levels. Using a rodent model, scientists identified various abnormalities in each brain region.
The study discovered several key molecular and neuronal anomalies in certain regions of the hippocampus that could be the cause of cognitive and emotional side effects.
“Following the legalization of cannabis, there is evidence of a reduction in perceived risks associated with cannabis use. There is a need to expand knowledge on the potential negative consequences of cannabis exposure during adolescence and this study addresses some of those gaps,” said Marta De Felice, lead study author and BrainsCAN postdoctoral researcher who stressed the need for crucial scientific evidence to inform public health policy.